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Banisteriopsis caapi, also known as Ayahuasca, Caapi or Yage, is a South American jungle vine of the family Malpighiaceae. It is used to prepare Ayahuasca, a decoction that has a long history of entheogenic uses as a medicine and "plant teacher" among the indigenous peoples of the Amazon Rainforest. It contains the beta-carboline harmala alkaloids and MAOIs harmine, harmaline, and tetrahydroharmine. The MAOIs in B. caapi allow the primary psychoactive compound, DMT (which is introduced from the other primary ingredient in Ayahausca, the Psychotria viridis plant), to be orally active. "The stems contain 0.11-0.83% beta-carbolines, of which 40-96% is harmine."[2] In South America, most caapi is cultivated by the shamans who use it, but most caapi available to buy on internet is wild Peruvian vines taken from the forest.[3]

According to The CRC World Dictionary of Plant Names by Umberto Quattrocchi, the naming of B. caapi was actually dedicated to John Banister, a seventeenth-century English clergyman and scientist. An earlier name for the genus Banisteriopsis was Banisteria, and the plant is sometimes referred to as Banisteria caapi in everyday usage.

The name Ayahuasca means "vine of the soul", and the shamans of the indigenous Western Amazonian tribes use the plant in religious and healing ceremonies. In addition to its hallucinogenic properties, caapi is used for its healing properties as a purgative, effectively cleansing the body of parasites and helping the digestive tract.

There are two scientifically accepted varieties

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