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Oncogenesis is the process of malignant transformation leading to the formation of a tumor (tumorigenesis). It is characterized by a progression of changes on cellular and genetic level that ultimately reprogram a cell to undergo uncontrolled cell division, thus forming a malignant mass. Hornberg, J., Binder, B., Bruggeman, F., Schoeber, B., Heinrich, R., Westerhoff, H., "Control of MAPK signalling from complexity to what really matters", Oncogene, Vol. 24, pp 5533-5542, (published online 20June2005).
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