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A pandemic (from Greek pa? pan all + d?ยต?? demos people) is an epidemic of infectious disease that spreads through human populations across a large region; for instance a continent, or even worldwide. According to the World Health Organization (WHO), a pandemic can start when three conditions have been met[citation needed] A disease or condition is not a pandemic merely because it is widespread or kills many people; it must also be infectious. For instance, cancer is responsible for many deaths but is not considered a pandemic, because the disease is not infectious or contagious (although certain cases of some types of cancer might be). There have been a number of significant pandemics recorded in human history, generally zoonoses which came about with domestication of animals, such as influenza and tuberculosis. There have been a number of particularly significant epidemics that deserve mention above the "mere" destruction of cities
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