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Patent medicine is the somewhat misleading term given to various medical compounds sold under a variety of names and labels, though they were, for the most part, actually medicines with trademarks, not patented medicines. In ancient times, such medicine was called nostrum remedium, "our remedy" in Latin, hence the name "nostrum," that is also used for such medicines; it is a medicine whose efficacy is questionable and whose ingredients are usually kept secret. The name patent medicine has become particularly associated with the sale of drug compounds in the nineteenth century under cover of colourful names and even more colourful claims. The promotion of patent medicines was one of the first major products of the advertising industry, and many advertising and sales techniques were pioneered by patent medicine promoters. Patent medicine advertising often talked up exotic ingredients, even if their actual effects came from more prosaic drugs. One memorable group of patent medicines — liniments that allegedly contained snake oil, supposedly a universal panacea — made snake oil salesman a lasting synonym for a charlatan.

The phrase patent medicine comes from the late 17th century[1] marketing of medical elixirs, when those who found favour with royalty were issued letters patent authorising the use of the royal endorsement in advertising. The name stuck well after the American Revolution made these endorsements by the crowned heads of Europe obsolete. Few if any of the nostrums were actually patented; chemical patents came into use in the USA in 1925, and in any case attempting to monopolize a drug, medical device, or medical procedure was considered unethical by the standards upheld during the era of patent medicine. Furthermore, patenting one of these remedies would have meant publicly disclosing its ingredients, which most promoters wanted to avoid.

Instead, the compounders of these nostrums used a primitive version of branding to distinguish themselves from the crowd of their competitors. Many familiar names from the era live on in brands such as Luden's cough drops, Lydia E. Pinkham's vegetable compound for women, Fletcher's Castoria, and even Angostura bitters, which was once marketed as a stomach remedy. Many of these medicines, though sold at high prices, were made from quite cheap ingredients. Their composition was well known within the pharmacy trade, and druggists would sell (for a slightly lower price) medicines of almost identical composition that they had manufactured themselves. To protect profits, the branded medicine advertisements laid great emphasis on the brand-names, and urged the public to accept no substitutes.

At least in the earliest days, the history of patent medicines is coextensive with the history of medicine itself. Empirical medicine, and the beginning of the application of the scientific method to medicine, began to yield a few effective herbal and mineral drugs for the physician's arsenal. These few tested and true remedies, on the other hand, were inadequate to cover the bewildering variety of diseases and symptoms. Beyond these patches of knowledge they had to resort to occultism; the "doctrine of signatures" — essentially, the application of sympathetic magic to pharmacology — held that nature had hidden clues to medically effective drugs in their resemblances to the human body and its parts. This led medical men to hope, at least, that, say, walnut shells might be good for skull fractures. Given the state of the pharmacopoeia, and patients' demands for something to take, physicians began making "blunderbuss" concoctions of various drugs, proven and unproven. These concoctions were the ancestors of the several nostrums.

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