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Polyketides are secondary metabolites from bacteria, fungi, plants, and animals. Polyketides are biosynthesized by the polymerization of acetyl and propionyl subunits in a similar process to fatty acid synthesis (a Claisen condensation). [1] They are the building blocks for a broad range of natural products or are further derivatized. Polyketides are structurally a very diverse family of natural products with diverse biological activities and pharmacological properties. Polyketide antibiotics, antifungals, cytostatics, anticholesterolemics, antiparasitics, coccidiostatics, animal growth promoters and natural insecticides are in commercial use.[citation needed] Polyketides are synthesized by one or more specialized and highly complex polyketide synthase (PKS) enzymes. [1] name="See_also" id="See_also">
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