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A septum (Latin something that encloses; plural Septa) is a partition separating two cavities or spaces. Examples include

Fungi produce septa to partition filamentous hyphae into discrete cells.

Histological septa are seen throughout most tissues of the body, particularly where they are needed to stiffen a soft cellular tissue, and they also provide planes of ingress for small blood vessels. Because the dense collagen fibres of a septum usually extend out into the softer adjacent tissues, microscopic fibrous septa are less clearly defined than the macroscopic types of septa listed above. In rare instances, a septum is a cross-wall.

The septum is also found within the chambers of the heart. It provides strength to the walls of the heart and separates the left and right sides of the heart.

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