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A sequela, (pronounced /s?'kwi?l?/, plural sequelæ) is a pathological condition resulting from a disease, injury, or other trauma.

Typically, a sequela is a chronic condition that is a complication of an acute condition that begins during the acute condition. This is in contrast to a late effect.

There are also sequelae which occur as a result of treatment for a disease. For instance, one sequela resulting from chemotherapy used to treat cancer may be "toxic peripheral neuropathy," a painful chronic condition which is usually controlled with medication. Not everyone who is treated with chemotherapy develops toxic peripheral neuropathy but it may occur when a bacterium has effected a biothermic rhythmatic condition such as coronary heart disease.

Some conditions may be diagnosed retrospectively from their sequelae. An example is pleurisy.

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