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Sporogenesis is the production of spores in biology. The term is also used to refer to the process of reproduction via spores. Reproductive spores are formed in many eukaryotic organisms, such as plants, algae and fungi, during their normal reproductive life cycle. Dormant spores are formed, for example by certain fungi and algae, primarily in response to unfavorable growing conditions. Most eukaryotic spores are haploid and form through cell division, though some types are diploid or dikaryons and form through cell fusion.

Reproductive spores are generally the result of cell division, most commonly meiosis (e.g. in plant sporophytes). Sporic meiosis is needed to complete the sexual life cycle of the organisms using it.

In some cases, sporogenesis occurs via mitosis (e.g. in some fungi and algae). Mitotic sporogenesis is a form of asexual reproduction. Examples are the conidial fungi Aspergillus and Penicillium, for which mitospore formation appears to be the primary mode of reproduction. Other fungi, such as ascomycetes, utilize both mitotic and meiotic spores. The red alga Polysiphonia alternates between mitotic and meiotic sporogenesis and both processes are required to complete its complex reproductive life cycle.

In the case of dormant spores in eukaryotes, sporogenesis often occurs as a result of fertilization or karyogamy forming a diploid spore equivalent to a zygote. Therefore, zygospores are the result of sexual reproduction.

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