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Toxicity is the degree to which something is able to produce illness or damage to an exposed organism. Toxicity can refer to the effect on a whole organism, such as a human or a bacterium or a plant, or to a substructure, such as a cell (cytotoxicity) or an organ (organotoxicity such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or "society at large".

In the science of toxicology, toxicity is the degree of impact of an external substance or condition and its deleterious effects on living things organisms, organ systems, individual organs, tissues, cells, subcellular units is the subject of study. A central concept of toxicology is that effects are dose-dependent; even water – generally not considered to be toxic – can lead to water intoxication when taken in large enough doses, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect.

Toxicity is the ability of a chemical or physical agent to induce detrimental temporary or permanent tissue change or to detrimentally interfere with normal biochemical processing.

There are generally three types of toxic entities; chemical, biological, and physical.

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